Mycobacterium tuberculosis from chronic murine infections that grows in liquid but not on solid medium
نویسندگان
چکیده
منابع مشابه
Mycobacterium tuberculosis from chronic murine infections that grows in liquid but not on solid medium
BACKGROUND Old, stationary cultures of Mycobacterium tuberculosis contain a majority of bacteria that can grow in broth cultures but cannot grow on solid medium plates. These may be in a non-replicating, dormant growth phase. We hypothesised that a similar population might be present in chronic, murine tuberculosis. METHODS Estimates of the numbers of viable M. tuberculosis, strain H37Rv, in ...
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OBJECTIVES Can the characteristics of persisters in cultures of Mycobacterium tuberculosis also be found in bacilli from the sputum of pulmonary tuberculosis patients? The objective of this study was to explore whether the ability of persisters to grow in liquid but not on solid culture media, as in 100 day static cultures, can also be found in bacilli in sputum. METHODS Serial dilutions of h...
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BACKGROUND Traditionally, the Lowenstein Jensen (LJ) medium has been used for culturing Mycobacterium tuberculosis. In abdominal tuberculosis (TB), the reported yield from tissue culture is between 20% and 60%. Liquid cultures are reported to give a higher yield but there is little data available in abdominal TB. AIM To compare the yield of TB culture with BACTEC 460TB liquid medium and LJ me...
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Attempts to improve the diagnosis of tuberculosis (TB) in high-burden countries has resulted in significant funding and initiatives to change the method of diagnosis of TB from light microscopy supplemented with X-ray to a sophisticated diagnostic algorithm based on the latest technological innovations. Such activities are overdue and should be welcomed, but the lack of skills and support avail...
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ژورنال
عنوان ژورنال: BMC Infectious Diseases
سال: 2004
ISSN: 1471-2334
DOI: 10.1186/1471-2334-4-51